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Male Infertility Treatment

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NSA- non surgical sperm aspiration
MESA-micro-surgical epididymal sperm aspiration
DNA fragmentation index

World over more than quite often every discussion or treatment of infertility revolves around the women. The reason might vary from culture to culture however the final result is not good for the couple.
Women are mostly open for discussion about their reproductive issues however men still hesitate to discuss and get treated.
The feeling of being left out in male partners is evident and the reason for this is lack of specialty clinics exclusively for male infertility.
HOPE is a complete male infertility center with purpose built facility, special operation theater, instruments, dedicated attached andrology laboratory, genetic laboratory, high powered magnifying microscopes and the expertise; all exclusively for male infertility.

We are sensitive to your needs and so we make you comfortable to discuss in complete confidentiality. We bring the most advanced knowledge in male reproductive science,andrology & embryology to make it possible for every man to father his own child even if he has been previously declared total sperm less (zero count).

HOPE is working on awareness program to make men understand their reproductive problems are solvable and not something to hide.

Quite often men (60%) who do not have sperm in ejaculate actually may have small zones of sperm production in the testicle. At HOPE we can reach to these microscopic zones of testicle where good graded sperms are available and these sperms can be used to fertilise the eggs.
TESE & TESA are some of the procedures that can be used depending on the needs of the couple.

NSA: Non Surgical Sperm Aspiration

These procedures are required mostly in couple with male factor infertility. It’s a minimal invasive procedure, less painful, done in local sedation & with quicker results.

MESA: Micro-surgical Epididymal sperm Aspiration

Quite often an optimal procedure to obtain sperms in cases of obstruction of the reproductive tract. It’s a relatively painless and minimal invasive procedure, which allows us to recover the best quality sperms which can be further used with IVF procedures.

This procedure requires a well skilled male infertility team, embryology laboratory, specialised equipments and an operating suite and lack of above mentioned combination makes MESA rarely done procedure quite often.

HOPE team has experience in countries where use of donor sperm is not allowed, hence procedures like TESA or MESA are the only options for males with low sperm count.


Since the testicular tubules are microscopic they cannot be judged by naked eye, hence a high powered operating microscope is used to find the healthier tubules so they can be extracted and sperms can be harvested from them for ICSI.

HOPE follows methodology recommended by EAA European association of andrologists.

Micro-TESE is an advanced procedure that requires a combination of a male infertility operating microscope, a much advanced embryology laboratory & an expert embryologist. This combination can make the difference between success and failure for any couple previously diagnosed with azoospermia.

Advances in reproductive science in last ten years have made it possible for men, who were previously declared sterile, to father biological children.

DNA Fragmentation Index

The usual test of semen called semen analysis is limited and it can’t assess DNA damage in sperm & we know sperms from even a normal semen analysis report can have high DNA damage, so evaluation of DNA damage in many cases becomes important.
Studies have shown that a man with DNA fragmentation percentage higher than 30% have has difficulty becoming a father (miscarriages).

This DNA damage can be due to many different reasons:

  • Long abstinence
  • Advanced age (after 46)
  • Smoking
  • Exposure to high level of pollutants
  • Exposure to high temperatures
  • Testicular trauma or cancer
  • Exposure to chemicals or radiation

We recommend DFI test for couples with:

  • Recurrent miscarriages
  • Recurrent implantation failures
  • Fertilisation failure
  • Low embryo quality

Due to various reasons fragmentation can occur in DNA and sperms with high index of such fragmented DNA leads to low quality zygotes or low number of implantations. There are assays that can give us a range value for the amount of DNA fragmentation occurred, this can be treated to some extend with some medicinal support however doing an ICSI with combination of TESE has showed quite promising results constantly.

Hope offers the latest inventions in field of male infertility, by which we no more need millions of sperm count but only a single sperm to let the man father his own child.


All communications are 100% confidential.